By Kenneth K. Carroll, David Kritchevsky
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Additional info for Nutrition and disease update. Cancer
In contrast, the inverse Copyright © 1994 AOCS Press 36 A. Catharine Ross gradient for vitamin C was highly significant. 64), it was not surprising that adjustment for vitamin C eliminated the effect of carotene. However, the opposite adjustment left the effect of vitamin C intact. Although most studies have not supported a relationship of vitamin C and lung cancer (NRC, 1989a), the authors pointed out that vitamin C intake in this population is generally low so that effects of higher intakes may have been more readily discerned.
However, the development of skin yellowing in the β-carotene-supplemented men prevented the trial from remaining double-blind. The appearance and size of leukoplakia and the percent of micronucleated cells were evaluated after 3 and 6 months. By 6 months, there was significant reduction in appearance and size of oral leukoplakia in the group supplemented with both β-carotene and vitamin A and a marginal reduction in those supplemented with β-carotene alone. The percent of micronucleated cells, an indicator of the genotoxic activity of areca constituents, was reduced very significantly after 3 months with either supplement.
And associated with dietary factors include: cancers Copyright © 1994 AOCS Press Vitamin A and Cancer 29 of the gastrointestinal, digestive tract (esophageal, stomach, pancreatic, and colorectal cancers), cancers associated with the reproductive organs (breast, endometrial, and ovarian cancers in women and prostate cancer in men) and lung, liver, and bladder cancer (NRC, 1989a). A. Vitamin A and Cancer: Conclusions of the Benchmark Reports There is substantive agreement, with some difference in emphasis, between the Surgeon General’s Report (USDHHS, 1988) and the report of the National Research Council (NRC, 1989c) regarding the evidence relating vitamin A and cancer, as is summarized below.
Nutrition and disease update. Cancer by Kenneth K. Carroll, David Kritchevsky