By Maeve Lowery
Written via professional oncologists focusing on pancreatic melanoma, Dx/Rx: Pancreatic melanoma is a concise pocket reference for all specialist caregivers of sufferers with pancreatic melanoma. this convenient consultant offers accomplished, updated details at the epidemiology, signs, analysis, and administration of malignancies of the pancreas. issues contain exact define of the analysis technique and staging, molecular pathogenesis, localized illnesses and complex circumstances, metastatic pancreatic melanoma, unusual pancreatic malignancies, and knowledge on supportive care. awarded in a quick-reference structure, Dx/Rx: Pancreatic melanoma is a necessary consultant for at the ward or within the health center.
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Additional info for Dx Rx: Pancreatic Cancer (Jones & Bartlett DX RX Oncology)
A) Main-duct IPMN. (b) Side branch IPMN. 15 MCN occurs almost exclusively in postmenopausal females, predominantly in the body and tail of the pancreas. 16 Treatment is surgical resection, with the prognosis dependent on the presence and depth of invasion of invasive cancer. Completely resected MCNs without dysplasia are generally considered cured. ■ References 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. Hezel A, Kimmelman A, Stanger B, et al. Genetics and biology of pancreatic ductal adenocarcinoma. Genes Dev.
2010 Pancreatic Adenocarcinoma Clinical Practice Guidelines in Oncology. indd 44 9/14/10 2:19 PM Localized Disease 45 12. 13. 14. 15. 16. 17. 18. 19. 20. 2010. org. Accessed 06/09/ 2010. org. NCCN Pancreatic Adenocarcinoma Panel recognize the work of the experts and adapt their criteria to define resectability status. Callery M, Chang K, Fishman EK, et al. Pretreatment Assessment of Resectable and Borderline Resectable Pancreatic Cancer: Expert Consensus Statement. Ann Surg Oncol. 2009;16: 1727–1733.
This suggests that the genetic status of a pancreatic carcinoma may predict widespread systemic failure and implies that advanced pancreatic cancer may encompass several distinct molecular subtypes associated with clinically distinct patterns of spread. Although many trials of systemic therapy have enrolled patients with both locally advanced and metastatic disease, there is now a move toward designing specific trials to evaluate optimal stage-specific therapy. ■ Use of Radiosensitizers for Chemoradiation ■ ■ 5-fluorouracil (5-FU) remains the most commonly used radiosensitizer used in combination with radiotherapy for pancreatic cancer and is the reference agent used in all early trials of chemoradiation.
Dx Rx: Pancreatic Cancer (Jones & Bartlett DX RX Oncology) by Maeve Lowery