Advances in Chemotheraphy. Volume 1 by Abraham Goldin PDF

By Abraham Goldin

ISBN-10: 1483199290

ISBN-13: 9781483199290

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This approach, in addition to providing valuable drugs, has yielded a wealth of information relating chemical structure and trypan­ ocidal activity for a great variety of compounds, but it has given little or no insight into the mechanism of drug action. As we have seen, presentday problems in the chemotherapy of trypanosomiasis differ greatly from those of fifty years ago. No longer is there an urgent need for a drug to combat an annual death rate of hundreds of thousands; the need is for more efficient prophylactic agents and for new drugs to attack drug-resistant variants.

And Rhoads, C. P. (1953). Bhod 8, 965. Davis, B. D. (1943). /. Clin. Invest. 22, 753. , and Evans, A. F. (1963). New Engl J. Med. 268, 221. Dougherty, T. , and White, A. (1943). Proc. Soc. Exptl Biol Med. 53, 132. , Diamond, L. , Mercer, R. , Sylvester, R. , and Wolff, J . A. ( 1 9 4 8 ) . New Engl J. Med. 238, 787. Fountain, J . , Hutchinson, D. J . , Waring, G. , and Burchenal, J . H. ( 1 9 5 3 ) . Proc. Soc. Exptl Biol Med. 83, 369. , III. (1962). Cancer Chemotherapy Kept. 16, 19. , III. (1963).

Hayes, D. , James, G. , Sodee, D. , Bundles, Ε. , Schroeder, L. , Wohnan, I. J . , Traggis, D. , and Taylor, R. (1961). Blood 18, 431. Freireich, E. J . (1963). Ann. Internal Med. 59, 931. Freireich, E . J . , III, and Karon, Μ. (1962). Cancer Chemotherapy Kept. 16, 183. Freireich, Ε . , III, Schroeder, L. , Wolman, I. , Burgert, E. , Mills, S. , Selawry, O. , Moon, J . , Gendel, B. , Spurr, C. , and Lee, S, (1963). Blood 21, 699. Gellhom, A. (1953). Cancer 6, 1030. , KHgerman, M. , and JaflFe, I.

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Advances in Chemotheraphy. Volume 1 by Abraham Goldin


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